Signs/symptoms Hyper IgM syndrome

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pneumocystis pneumonia



infection/pneumocystis pneumonia (pcp), common in infants hyper igm syndrome, serious illness. pcp 1 of frequent , severe opportunistic infections in people weakened immune systems. many cd40 ligand deficiency first diagnosed after having pcp in first year of life. fungus common , present in on 70% of healthy people’s lungs, however, hyper igm patients not able fight off without administration of bactrim)
hepatitis (hepatitis c)
chronic diarrhea
hypothyroidism
neutropenia
arthritis
encephalopathy (degenerative)




^ x-linked immunodeficiency hyper igm clinical presentation: history, physical, causes . emedicine.medscape.com. retrieved 27 november 2016. 
^ davies, e graham; thrasher, adrian j (27 november 2016). update on hyper immunoglobulin m syndromes . british journal of haematology. 149 (2): 167–180. doi:10.1111/j.1365-2141.2010.08077.x. issn 0007-1048. pmc 2855828 . 
^ etzioni, amos; ochs, hans d. (1 october 2004). hyper igm syndrome—an evolving story . pediatric research. 56 (4): 519–525. doi:10.1203/01.pdr.0000139318.65842.4a. issn 0031-3998. 






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